Answering the Question of Ivermectin Overdose

Executive Summary

  • There are many questions related to whether is Ivermectin safe for humans, and a lot of inaccurate information is provided by health authorities.
  • This article covers the real story of Ivermectin safety and the potential for Ivermectin overdose. 

Introduction

On the question of is Ivermectin safe for humans and the potential for Ivermectin overdose to keep people from taking Ivermectin, as it would have cannibalized the sales of far more expensive on-patent medications with far lower side effects, the health authorities, under the control of the pharmaceutical companies, massively exaggerated the safety issues with Ivermectin. A good example of this is the FDA’s warning on Ivermectin, which you can read here. That article focuses on whether Ivermectin safe for covid — however, this website covers the use of Ivermectin for many purposes. All of the health authorities want Ivermectin only limited for use against parasites. This article covers the is Ivermectin safe without any pharmaceutical influence or any political considerations.

Is Ivermectin Safe for Humans, and the Potential for Ivermectin Overdose

This quote is consistent with all of the studies we have read on Ivermectin.

Moreover, there were almost no adverse effects for ivermectin treatment. Ivermectin exerts selective toxicity and has protective effect. – Anti-parasite drug ivermectin can suppress ovarian cancer by regulating lncRNA-EIF4A3-mRNA axes

And this quote.

Ivermectin has continually proved to be astonishingly safe for human use. Indeed, it is such a safe drug, with minimal side effects, that it can be administered by non-medical staff and even illiterate individuals in remote rural communities, provided that they have had some very basic, appropriate training. This fact has helped contribute to the unsurpassed beneficial impact that the drug has had on human health and welfare around the globe, especially with regard to the campaign to fight Onchocerciasis. Since the inception of the Mectizan Donation Programme, Merck has donated well over 2.5 billion Mectizan® tablets for Onchocerciasis treatment, with in excess of 700 million treatments authorised. Currently, some 80–90 million people are taking the drug annually through MDA in Africa, Latin America and Yemen. A further 300 million total treatments have been approved for lymphatic filariasis, with around 90 million treatments being administered annually (Fig. ​(Fig.8 ).8 ). At present 33 countries are receiving ivermectin for Onchocerciasis and 15 for Lymphatic filariasis. Consequently, around US$4 billion worth of ivermectin tablets have been donated to date. – Ivermectin, ‘Wonder drug’ from Japan: the human use perspective

The establishment media makes a massive deal of Ivermectin overdose. This is a scare tactic because not only is Ivermectin one of the safest drugs, but it takes a significant multiple of the recommended dose to end up with complications. See the following quote.

See the following quote.

Significant lethality was observed in mice and rats after single oral doses of 25 to 50 mg/kg and 40 to 50 mg/kg, respectively. No significant lethality was observed in dogs after single oral doses of up to 10 mg/kg. Significant lethality was observed in mice and rats after single oral doses of 25 to 50 mg/kg and 40 to 50 mg/kg, respectively. No significant lethality was observed in dogs after single oral doses of up to 10 mg/kg. – RXList

Let us explain how much of a multiple this is.

These are all in kg. And the recommended dose when in kg is .2 per kg.

Let us take the midrange value of (25 + 50)/2 = 37.5 + (40 + 50)/4 = 45. Let us take the midrange value of the first range provided. We get this by performing the following math.