How Ivermectin Improves the Immune Response by Acting as an Immunomodulator

Executive Summary

  • Immunomodulation is the control of the response of the immune system to threats.
  • This is what Ivermectin has proven to do to improve the immune system.

Introduction

A critical benefit of Ivermectin is its impact on moderating and optimizing the immune system’s response.

Understanding Immunomodulation

Immunomodulation is the calibration of the immune system so that it responds appropriately.

Problem #1: An Under-Responsive Immune System

When the immune system does not respond strongly enough, then sickness ensues. For example, “immunocompromised” cannot fight off infection, illness, etc.

Problem #2: An Over-Responsive Immune System

On the other side of the spectrum, when the immune system overreacts, it will attack healthy cells.

When this occurs, it is called an autoimmune disease. The category of autoimmune disease is just the organ or area of the body that the immune system attacks. However, all autoimmune diseases stem from an overreactive immune system attacking the body’s cells.

The immune system must constantly differentiate between the body’s cells and invading cells; the immune system loses this ability under autoimmune disease.

Optimizing The Immune Response

The immune system is extraordinarily complicated. Even the field of immunology does not have a firm grasp of how the immune system works. It is more accurate to say they understand the broad outlines. The immune system can be pushed “too high” or “too low” depending on stress and many factors that are only partially understood by medicine.

Video #1: Immune System Introduction

This is Kurzgesagt’s introductory video to the immune system.

This video does a great job of explaining how immunity is an emergent property of many different parts working in concert in extraordinary complexity. 

  • Ivermectin has been repeatedly demonstrated to be an immunomodulator.
  • Immunomodulation is a primary factor in fighting cancer as it optimizes the immune response, and thus, the proper immune response is critical for preventing and treating cancer.

The Immunomodulation Benefit in Cancer Reduction

The following quote is from the article at I2B.

Ivermectin’s mechanism of action is not limited to a single effect, in fact, the reason why it is possibly effective as a cancer therapy is that it has multiple, powerful, anti-tumor effects.

These include inhibition of the cell proliferation, prevention of invasion and metastasis, inducing apoptosis, and, as we saw with checkpoint blockade therapy, it can also induce an immune response when needed.

As for the last point, Ivermectin’s function as an immunomodulatory agent is well known. This means optimizing the immune system’s response to neither overreact nor underreact.

Conclusion

Ivermectin has beneficial effects not only for cancer — as one of the mechanisms of how Ivermectin works is improving the immune system, which means it improves the immune system against cancer and other diseases. When you strengthen your immune response, you improve it against all threats.

We cover the use of ivermectin versus cancer at our subscription website.