Is Joe Biden’s Mental Decline Due to Lupron?

Executive Summary

• This article investigates how much of Joe Biden’s mental decline is most likely related to hormone therapy that was used to treat Joe Biden’s prostate cancer, which had been hidden from public view.

Introduction

Lupron is a very widely prescribed drug that has uses ranging from prostate cancer hormone therapy to puberty blockers.

Lupron’s side effects are serious (covered in the article at Part 2: The Highly Problematic Reviews of Lupron.)

The announcement that Joe Biden had a very advanced stage of prostate cancer in May of 2025 and the fact that this prostate cancer would usually be treated with a testosterone-blocking drug such as Lupron (along with other treatments like chemotherapy and or radiotherapy) or similar brings up the question of how much of Joe Biden’s decline is due to this treatment protocol. His prostate cancer was declared “hormone-receptive,” and a likely treatment would be either Lupron or a drug like Lupron. For years, people have wondered why Biden’s mental acuity has declined so significantly that he seemed to be a candidate for assisted living.

The Description of Biden’s Treatment

This is how CBS described the potential treatment in the article Breaking down Biden’s prostate cancer diagnosis — here’s what to know about the disease.

Based on what is known about his diagnosis, the primary treatment would be to block testosterone with a medication like Lupron, she said. This might be combined with other hormone therapies like Zytiga, or even chemotherapy, depending on the specific case.

This is describing a potential future treatment; however, in reality, Biden has probably had this prostate cancer diagnosis for between 4 and 10 years, therefore, this treatment is probably describing the treatment he has already had. Dr. Drew explains his view of how Biden’s prostate cancer was hidden from the public for years.

Dr. Drew on How Long Biden Had Prostate Cancer

This means that it is very likely that Biden has been receiving these treatments for years, which means that Biden has been expected to be on Lupron for this time.

The Common Alzheimer’s Systems Caused by Lupron and Other Similar Testosterone Suppressing Drugs

The following video discusses the adverse cognitive effects of drugs like Lupron.

Because of the significant side effects of hormone therapy, it is essential to analyze whether the claimed hypothesis that testosterone promotes prostate cancer is true.

Important Point #1: Lupron and Alzheimer’s Symptoms

At the 9:55 mark of the video, Dr. Schulz states that it can be shown that people have reduced mental performance while they are on testosterone blockers.

He does seem to try to walk around this issue and state that it is just related to the reduced testosterone.

However, the fact is that the reduction in memory and mental function is a fact for people who are on testosterone blockers.

Furthermore, contrary to what Dr. Schulz states in this video, a substantial portion of this reduced function is permanent. This comment on this video contradicts Dr. Schulz’s proposal.

Comment #1: Testosterone Never Came Back?

I was on Eligard for four months while undergoing my radiation treatments.

My testasterone never came back…even after three years, I am not even in the Low range.

My PSA has been undetectable for three years now.

That is what happens when your prostate gets annihilated by radiation.

And my Doc is thinking about prescribing me testasterone. I am 71 and have no energy at all. All kinds of problems three years after…had a stricture removed by a erethotomy and now must self-cath every fifth day to keep the scar tissue from returning.

I am also seeing a Pelvic Floor therapis because I now have perineum pain and urgency to pee…every single hour. I just get very little sleep and am in constant pain.

The life I knew is over.

Gee…that seems to contradict Dr. Schulz’s statement.

Comment #2: The Patient’s Testicles Vanished?

My PSA was 5000 when I was told I had advanced prostate cancer. In most of my lymph nodes. With Lupron shots my PDA when last tested was 0.45. But then my testicles almost vanished so not surprised,!

How do testicles grow back — as these are the major organs that produce testosterone?

Yes I have little energy but that started from a bad heart with failed quad bypass and with a pacemaker.

The worst is day long sweats that I need my head wrapped in a towel. Soaked Tee shirts every few hours. Make like miserable. At 76 should I just stop the shots and hope the sweats go away. Already on pain med every four hours.

Comment #3: Remembering to Get Eggs When Opening the Fridge While on Lupron?

Stop downplaying the horrific effect that ADT CASTRATION has on mental function.

ADT is another name for this type of treatment — it stands for androgen deprivation therapy.

Horrific Brain Fog?

The brain fog is so horrific that it is actually unsafe to operate a vehicle and the effect lasts months or years after the ADT toxic shots are supposed to expire. You likely will no longer be able to multitask and it will even be difficult to concentrate on one task at a time.

Keep Repeating Eggs to Concentrate?

Making breakfast, you open the fridge door and don’t remember what you wanted to get. You have to constantly repeat to yourself EGGS, EGGS EGGS.