The Testing Evidence for Carboplatin Chemotherapy

Executive Summary

  • Carboplatin is presented as effective against cancer by medical authorities and cancer centers.

  • How accurate is this presentation?

Introduction

Carboplatin is a major chemotherapy drug.

What cancer centers, oncologists, and medical authorities don’t do is explain the actual effectiveness of Carboplatin for chemotherapy.

Common Side Effects

The following quote is from Cancer Research UK, a biased website is just a business development front end for the chemotherapy treatment business.

Feeling or being sick
Feeling or being sick is usually well controlled with anti sickness medicines. Avoiding fatty or fried foods, eating small meals and snacks, drinking plenty of water, and relaxation techniques can all help.

It is important to take anti sickness medicines as prescribed even if you don’t feel sick. It is easier to prevent sickness rather than treating it once it has started.

Changes to how your liver works
You might have liver changes that are usually mild and unlikely to cause symptoms. They usually go back to normal when treatment finishes. You have regular blood tests to check for any changes in the way your liver is working.

Kidney damage
To help prevent kidney damage, it is important to drink plenty of water. You might also have fluids into your vein before, during and after treatment. You have blood tests before your treatments to check how well your kidneys are working.

Tummy (abdominal) cramps and pain
Tell your treatment team if you have this. They can check the cause and give you medicine to help.

Low level of minerals in the blood
Carboplatin can cause low levels of minerals such as sodium, potassium, calcium and magnesium in your blood. Some minerals are more likely to cause symptoms than others. Low calcium and magnesium could cause muscle cramping or twitching. In most cases low mineral levels are picked up on blood tests.

You have regular blood tests during treatment to check this.

And what must be compared against this truncated listing of the side effects is that this type of chemotherapy has a poor history of effectiveness.

The Establishment Explanation of Chemotherapy

This video explains how chemotherapy works and does explain some of the negative aspects of chemotherapy. However, anyone can propose a hypothesis of how the mechanism works — particularly after a treatment has been around for decades, it is not only the mechanism that must be explained, but there must be strong evidence that the treatment works. The proposed improvement explained in this video is primarily due to pharmaceutical companies rigging the math. 

How the Reality of Chemotherapy is Hidden from the Public

The problems with chemotherapy became apparent nearly immediately after the discovery of chemotherapy — or the use of mustard gas as a treatment against cancer. This is explained in the following quotation.

“If one reads the literature of the time, there was a real sense of excitement that perhaps drugs could cure patients with cancer,” Vincent DeVita, Jr., the prominent oncologist, wrote of the first widespread use of nitrogen mustard as a chemother- apeutic agent. Sadly, after the drug was widely distributed and some time had passed, the excitement proved premature. The remissions induced by nitrogen mustard turned out to be brief and incomplete. The drug was able to”soften” the typically hard nodes for only a matter of weeks.

The cancer then sprang back to life, again packing the lymph nodes full of solid malignancy. It was a blow to the fragile, tantalizing hope for chemotherapy.
The euphoria was followed by pessimism, and the prospect of drugs affecting the outcome for cancer patients in any meaningful way was again shrouded in uncertainty.

However, not only is the origin of chemotherapy as mustard gas not explained to the public, but the apparent limitations of chemotherapy are also not explained.

Oncology Drugs Average of Less Than Three Months Improvement in Increased Lifespan

A 2017 paper published in JAMA Oncology presented some stunning conclusions. Of sixty-two new oncology drugs approved between 2003 and 2013, only 43 percent offered a survival benefit of three months or longer, 11 percent offered a survival benefit of less than three months, 15 percent had an unknown survival benefit, and 30 percent offered no survival benefit at all.

45% of Oncology Drugs Reduce Patient Safety

Furthermore, 45 percent were associated with reduced patient safety. A 2017 study published in the British Medical Journal (BMJ) that looked at the survival and quality-of-life benefits of forty-eight cancer drugs approved in Europe by the European Medicines Agency (EMA) between 2009 and 2013 reached similar conclusions: “This systematic evaluation of oncology approvals by
the EMA in 2009–13 shows that most drugs entered the market without evidence of benefit on survival or quality of life. At a minimum of 3.3 years after market entry, there was still no conclusive evidence that these drugs either extended or improved life for most cancer indications. When there were survival gains over existing treatment options or placebo, they were often marginal.”