The Testing Evidence for Using Ivermectin for Treating Leukemia or Blood Cancer
Executive Summary
- This article covers the evidence I could find for Ivermectin as a treatment for Leukemia.
Article Summary
Studies demonstrate that Ivermectin is effective against cancer, we then cover how Ivermectin works against cancer by explaining the mechanisms of action, and then the impacts of Ivermectin on cancer.
Introduction
This article provides an overview covering the evidence for Ivermectin versus Leukemia.
In many articles on this site, such as the article How Ivermectin Is Useful for Treating Cancer we covered the evidence for the benefits of Ivermectin for cancer. However, the topic of which specific cancers Ivermectin has been proven effective is a constant source of questions.
There are a lot of quotes in this article, but I have a short one for each cancer type. The article uses the term “IVM” to mean Ivermectin.
What is the Interest Level in the Search Topic Ivermectin Brain Cancer?
The search for Ivermectin Brain Cancer is currently one of the most frequently searched cancer types concerning Ivermectin. After reviewing the available articles on the Internet, we found there is very little coverage of the effectiveness of Ivermectin for many specific types of cancer. In response, we created articles covering the effectiveness of Ivermectin for nearly all of the different cancers including Ivermectin Brain Cancer. You can see our full list of articles on the topic of Ivermectin versus the different cancers at The Cancers For Which Ivermectin Has Been Demonstrated to be Effective.
About the Brightwork Research Treatment Database
We have a subscription website that provides people with everything they need to know about using Ivermectin for several diseases. Cancer is just one of our most researched areas. To see more see the below article indexes.
Article Indexes
- Open this link to see just one example Ivermectin article index.
- Open this link to see the full article index.
We have the most research on Ivermectin and Ivermectin for cancer and are completely independent. However, we have to charge subscribers to stay independent. We have free articles that expose readers to our research and writing -- however most of our content is behind a paywall.
What is the Interest Level in the Search Topic Ivermectin Leukemia and Ivermectin Blood Cancer?
The search for Ivermectin Leukemia and Ivermectin Blood Cancer is currently the most frequently searched cancer type concerning Ivermectin. After reviewing the available articles on the Internet, we found there is very little coverage of the effectiveness of Ivermectin for many specific types of cancer. In response, we created articles covering the effectiveness of Ivermectin for nearly all of the different cancers including Ivermectin Leukemia and Ivermectin Blood Cancer. You can see our full list of articles on the topic of Ivermectin versus the different cancers at The Cancers For Which Ivermectin Has Been Demonstrated to be Effective.
About the Brightwork Research Treatment Database
We have a subscription website that provides people with everything they need to know about using Ivermectin for several diseases. Cancer is just one of our most researched areas. To see more see the below article indexes.
Article Indexes
- Open this link to see just one example Ivermectin article index.
- Open this link to see the full article index.
We have the most research on Ivermectin and Ivermectin for cancer and are completely independent. However, we have to charge subscribers to stay independent. We have free articles that expose readers to our research and writing -- however most of our content is behind a paywall.
Cancer Type #5: Hematological Cancer, or Blood Cancer, or Leukemia
Leukemia is a type of malignant clonal disease caused by abnormal hematopoietic stem cells [52]. In an experiment designed to screen potential drugs for the treatment of leukemia, IVM preferentially killed leukemia cells at low concentrations without affecting normal hematopoietic cells [51]. The mechanism was related to the increase in the influx of chloride ions into the cell by IVM, resulting in hyperpolarization of the plasma membrane and induction of reactive oxygen species (ROS) production. It was also proven that IVM has a synergistic effect with cytarabine and daunorubicin on the treatment of leukemia. Wang’s experiment found that IVM could selectively induce mitochondrial dysfunction and oxidative stress, causing chronic myeloid leukemia K562 cells to undergo increased caspase-dependent apoptosis compared with normal bone marrow cells [53]. It was also confirmed that IVM inhibited tumor growth in a dose-dependent manner, and dasatinib had improved efficacy.
In an experiment designed to screen potential drugs for the treatment of leukemia, IVM preferentially killed leukemia cells at low concentrations without affecting normal hematopoietic cells. – NIH
Regarding the dosage and sourcing of Ivermectin, see the article On the Topic of Ivermectin Dosage and Sourcing.
Why Are Anti Parasitic Drugs Effective Against Cancer?
To understand why this class of drugs works against cancer, see the article The Mechanism of How Anti-Parasitic Drugs Work to Mitigate Cancer.
The Mechanisms by Which Ivermectin Works Against Cancer
Confidence in Ivermectin being effective for many cancer types also comes from understanding the specific mechanisms by which Ivermectin works against cancer. I cover this topic in detail in the article By How Many Different Mechanisms Does Ivermectin Fight Cancer?
More About The C19Early Clinical Trial Comparison Website
The C19early.com website tracks clinical trials. It is the best source of information on the studies of the effectiveness based upon clinical trials of different treatments for covid. However, it is more than this - as it is a model for how clinical trials should be communicated to the public so the extraordinarily corrupt medical establishment does not control the information. And it is the website that the medical establishment would like banned from the Internet.
One of the things the C19Early website showed was that early treatment significantly impacted the outcomes against covid.
The Benefit of Early Treatment
Notice that the earlier the treatment is used, the better the outcomes. Naturally, early treatment is measured in days with a respiratory disease like COVID-19, while in months with a disease like cancer. So the timings are different, but the principle is the same.
Even though this website does not track cancer clinical trials (unfortunately, no website does), the site holds essential observations. For one, a person's response to covid is like their response to cancer, greatly dependent upon the strength and health of their immune system.
Things like Zinc, Ivermectin, and Fenbendazole all empower the immune system and are, therefore, effective in the treatment and prevention of both COVID and cancer.
Offering Cancer Prevention as Well as Treatment
What is better than treatment is prevention. For anyone who is concerned with cancer prevention, both a very healthy lifestyle and diet, as well as things like Ivermectin and or Fenbendazole, are things that can be taken both as a treatment and as a preventative. We cover all these topics and the supporting specifics on our subscription website.
Impacts of Ivermectin on Cancer
The following are how Ivermectin works against cancer.
Impact #1: Inhibiting Proliferation of Tumor Cells
Recently, ivermectin has been reported to inhibit the proliferation of several tumor cells by regulating multiple signaling pathways.
The Ivermectin blocking of PAK1 proteins, aka activated kinase, is a reason for this.
The instrumentality of PAK1 in cancer growth is explained in the following quotation from the article Ivermectin: enigmatic multifaceted ‘wonder’ drug continues to surprise and exceed expectations.
Impact #2: Inhibiting Metastasis
Ivermectin has powerful antitumor effects, including the inhibition of proliferation, metastasis, and angiogenic activity, in a variety of cancer cells.
Metastasis is how cancer spreads, and I cover this in detail in the article How Does Metastasis Work in the Body?
Impact #3: Promoting Apoptosis & Pyropoptsis
ivermectin promotes programmed cancer cell death, including apoptosis, autophagy, and pyropoptosis. Ivermectin induces apoptosis and autophagy is mutually regulated. Second, IVM seems to induce mixed cell death in tumor cells, which is also a controversial issue
A significant issue with the dysfunction of cancer is that the cancerous cells refuse instructions from the immune system to commit suicide -- or what is scientifically referred to as apoptosis. I cover apoptosis in the article How Ivermectin Improves Cancer Prevention and Treatment Through Improving Apoptosis or Programmed Cell Death.
Pyropoptosis is a type of apoptosis that is caused by inflammation.
Impact #4: Promoting Autophagy
Deng found that IVM could activate the nuclear translocation of TFE3 and induce autophagy-dependent cell death by dephosphorylation of TFE3 (Ser321) in SK-MEL-28 melanoma cells.
Autophagy clears away cells and recycles them. Different things can trigger more autophagy. I cover autophagy in the article Is Autophagy Effective Against Cancer?
Impact #5: Inhibit Cancer Cell Proliferation Through Inhibiting YAP1 Activity
Lung cancer has the highest morbidity and mortality among cancers. Nishio found that IVM could significantly inhibit the proliferation of H1299 lung cancer cells by inhibiting YAP1 activity.
Conclusion
There is ample evidence that Ivermectin is helpful against many different types of cancers. It is unlikely that these are the only cancers for which Ivermectin is effective, but the studies we have found so far show that Ivermectin works to combat and prevent it. Ivermectin is an immuno-modulator, so it has beneficial effects not only for cancer -- as one of the mechanisms of how Ivermectin works is improving the immune system, which means it improves the immune system against cancer and other diseases.
Regarding the dosage and sourcing of Ivermectin, see the article On the Topic of Ivermectin Dosage and Sourcing.
Why Are Anti-Parasitic Drugs Effective Against Cancer?
To understand why this class of drugs works against cancer, see the article The Mechanism of How Anti-Parasitic Drugs Work to Mitigate Cancer.
About Our Ivermecting Testing Program and Recommended Ivermectin Source of Supply
- We performed pharmaceutical testing on Ivermectin to find a lower-cost version that also matched Merck's original Ivermectin in bioequivalence.
- You can read about the details of our Ivermectin testing in this article, Our Ivermectin Bioequivalence Testing.
- We got Summit Products to carry this version of Ivermectin, which passed our bioequivalence testing.